Mesotherapy with PDRN: The Injectable Skin Booster for Radiance & Repair
Blogs15 April, 2025

“Wake up dull, damaged skin with the regenerative power of Polynucleotides”.

What Is Mesotherapy with PDRN?

Mesotherapy is a minimally invasive cosmetic procedure that involves injecting a customised blend of active ingredients directly into the mesoderm, the middle layer of the skin. This targeted technique allows for deep hydration, nutrient delivery, and cellular repair where it matters most. It’s a popular solution for revitalising skin from within—without the need for surgery or aggressive downtime.

When this treatment is combined with PDRN (Polydeoxyribonucleotide)—a regenerative compound derived from salmon DNA—it takes skin rejuvenation to the next level. Clinically proven for its powerful ability to stimulate tissue repair, enhance skin elasticity, and support collagen regeneration, PDRN is widely recognised in the fields of dermatology and aesthetics for its effectiveness and safety.

How Does It Work?

Mesotherapy with PDRN is performed in a series of simple yet strategic steps:

  1. A numbing cream is first applied to the treatment area to ensure comfort throughout the procedure.

  2. A bespoke cocktail containing PDRN—often combined with other skin boosters like hyaluronic acid or peptides—is then gently injected across the skin using either ultra-fine needles or a mesotherapy gun.

  3. As the solution is dispersed across the dermis, it begins working immediately to activate cellular regeneration, boost hydration, and improve the skin’s texture and resilience from within.

PDRN works by interacting directly with DNA receptors in skin cells, promoting tissue recovery, reducing inflammation, and enhancing skin metabolism. This makes it ideal for tired, aging, or damaged skin in need of deep restoration.

Why Choose PDRN Mesotherapy?

PDRN is far more than just another hydrating ingredient. Backed by extensive clinical research in the fields of wound healing and dermatologic regeneration, PDRN offers multi-dimensional skin support. Its key benefits include:

  • Accelerated tissue repair and healing

  • Increased collagen and elastin production

  • Strengthened skin barrier function

  • Smoother, more even skin tone and texture

  • Reduction in fine lines, redness, and scarring

  • Deep, long-lasting hydration that revitalizes from within

Unlike traditional hyaluronic acid treatments that mainly plump the surface, PDRN works on a cellular level, improving the overall health and function of the skin—not just its appearance.

Who Is It For?

PDRN Mesotherapy is suitable for a wide range of skin types and concerns. It is particularly beneficial for:

  • Dull, tired, or thinning skin

  • Early signs of aging, such as fine lines or reduced elasticity

  • Damaged or sensitized skin barriers

  • Post-acne marks, pigmentation, or redness

  • Those looking for a radiant boost before special events

  • Clients with dry, dehydrated, or sensitive skin

Treatment areas commonly include the face, neck, décolleté, and even under the eyes, where delicate skin often shows fatigue or aging first.

What to Expect

  • Duration: Each session lasts around 30 to 45 minutes

  • Comfort: Minimal discomfort thanks to numbing cream

  • Downtime: 1–3 days of mild redness or swelling

  • Results: Noticeably smoother, plumper, and more radiant skin in 5–7 days

  • Recommended course: A series of 3 to 4 sessions spaced 2 to 4 weeks apart for optimal, long-lasting results

Glowing Skin Starts Below the Surface

Mesotherapy with PDRN is more than a cosmetic refresh—it’s a medical-grade skin booster designed to transform your complexion from the inside out. It delivers real, lasting improvement in skin health, structure, and radiance

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